Establishing MIC breakpoints for coagulase-negative staphylococci to oxacillin
نویسندگان
چکیده
منابع مشابه
Correlation of oxacillin MIC with mecA gene carriage in coagulase-negative staphylococci.
The National Committee for Clinical Laboratory Standards has recently changed the oxacillin breakpoint from >/=4 mg/liter to >/=0. 5 mg/liter to detect methicillin-resistant coagulase-negative staphylococci (CoNS) because the previous breakpoint lacked sensitivity. To determine the correlation between the new oxacillin breakpoint and the presence of the mecA gene, 493 CoNS of 11 species were te...
متن کاملClinical validation for oxacillin susceptibility testing of coagulase negative staphylococci.
Oxacillin susceptibility of coagulase negative staphylococci as assessed by conventional methods was confirmed by a modified Etest method, extended to detect heteroresistance. Verification of susceptibility was followed by successful treatment for six consecutive children with deep seated infections. Physicians' trust in such a validated method will contribute to the appropriate use of antibiot...
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A total of 398 consecutive clinical staphylococcus isolates, of which 205 were coagulase negative and 193 were coagulase positive, were tested in parallel by using AutoMicrobic system Gram-Positive Susceptibility-MIC cards and modified Mueller-Hinton agar containing 4% NaCl and oxacillin (6 micrograms/ml). The AutoMicrobic system cards correctly detected 103 of 104 (99%) oxacillin-resistant coa...
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The biochemical profiles obtained with Staph-Ident (Analytab Products, Plainview, N.Y.) panels were combined with the results of adherence and synergistic hemolysis tests to define biotypes among 1,064 clinical isolates representing eight species of coagulase-negative staphylococci. The 672 isolates of Staphylococcus epidermidis were aligned in 69 of 144 potential biotypes in our scheme because...
متن کاملCoagulase-negative staphylococci.
The definition of the heterogeneous group of coagulase-negative staphylococci (CoNS) is still based on diagnostic procedures that fulfill the clinical need to differentiate between Staphylococcus aureus and those staphylococci classified historically as being less or nonpathogenic. Due to patient- and procedure-related changes, CoNS now represent one of the major nosocomial pathogens, with S. e...
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ژورنال
عنوان ژورنال: Journal of Antimicrobial Chemotherapy
سال: 2000
ISSN: 1460-2091,0305-7453
DOI: 10.1093/jac/45.2.259